After 50 Years of Chemo, One Biotech Could Lead the Next Cancer Breakthrough

For decades, toxic chemotherapy defined cancer care. This biotech's innovative approach could finally change that. With early results showing precision without poison, this story is one investors will want to see early.

AP Business News Digest

MICHELLE CHAPMAN
November 03, 2025

Here are the AP's top business stories that have moved or are planned to move today. All times U.S. Eastern. For up-to-the minute information on AP's coverage, visit AP Newsroom's Coverage Plan.

US--OpenAI-Amazon

OpenAI and Amazon sign $38B deal for AI computing power

SUMMARY: OpenAI and Amazon have signed a $38 billion deal to run OpenAI's systems on Amazon's cloud services. OpenAI will access hundreds of thousands of Nvidia's AI chips through Amazon Web Services. The deal was announced Monday, just days after OpenAI changed its partnership with Microsoft. Last week, California and Delaware regulators allowed OpenAI to move forward with a new business structure to raise capital and make a profit. Amazon stated that the demand for computing power has surged due to AI advancements. OpenAI will start using AWS immediately, with plans to expand further by 2027.

WORDS: 171 - MOVED: 11/03/2025 9:28 a.m. EST

https://newsroom.ap.org/detail/OpenAIandAmazonsignBdealforAIcomputingpower/071e752773dee5713c8b1a10039d08aa/text

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EU--France-Shein-Childlike Sex Dolls

France threatens to block Shein over sale of childlike sex dolls ahead of Paris store opening

SUMMARY: French authorities are threatening to ban access to Shein after discovering the e-commerce site sold childlike sex dolls. France's consumer watchdog found the dolls last week, stating they had a child-pornographic nature. The matter has been referred to public prosecutors. Economy minister Roland Lescure said he would call for a ban if it happens again. The watchdog sent a formal notice to Shein, urging prompt action. Shein, founded in China in 2012, is facing criticism for labor practices and environmental issues. The company is set to open its first permanent shop in Paris.

WORDS: 381 - MOVED: 11/03/2025 6:31 a.m. EST

https://newsroom.ap.org/detail/FrancethreatenstoblockSheinoversaleofchildlikesexdollsaheadofParisstoreopening/0ea6afe1594f87fe37afb6a4e64ba4f8/text

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US--Kimberly-Clark-Kenvue

Tylenol, Kleenex, Band-Aid and more put under one roof in $48.7 billion consumer brands deal

SUMMARY: Kimberly-Clark is buying Tylenol maker Kenvue in an approximately $48.7 billion cash-and-stock deal, creating a massive consumer health goods company. Kenvue shareholders will receive $3.50 per share in cash and 0.14625 Kimberly-Clark shares for each Kenvue share held at closing. That amounts to $21.01 per share, based on the closing price of Kimberly-Clark shares on Friday.

WORDS: 428 - MOVED: 11/03/2025 7:21 a.m. EST

https://newsroom.ap.org/detail/TylenolKleenexBandAidandmoreputunderoneroofinbillionconsumerbrandsdeal/98d5fd39c12b25524e3188da2e840436/text

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Financial Markets

Wall Street futures march higher as deal making takes spotlight from corporate earnings

SUMMARY: U.S. futures followed global markets higher ahead of another big week of corporate earnings reports but an absence of economic data as the U.S. government shutdown entered its second month. Futures for the S&P 500 gained 0.3% before the bell Monday, while Nasdaq futures advanced 0.6%. Futures for the Dow Jones Industrial Average bounced back-and-forth between tiny gains and losses. Kimberly-Clark shares slid more than 15% after the it announced that it was acquiring Tylenol maker Kenvue in a cash-and-stock deal worth about $48.7 billion, creating a massive consumer health goods company. Kenvue shares jumped 19% on the news.

WORDS: 603 - MOVED: 11/02/2025 11:23 p.m. EST

https://newsroom.ap.org/detail/WallStreetfuturesmarchhigherasdealmakingtakesspotlightfromcorporateearnings/66f005545f7797d2831237efbd07c736/text

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US--Microsoft-AI Chips

Microsoft enters approximately $9.7B contract with IREN that gives it access to Nvidia chips

SUMMARY: Microsoft has entered into an approximately $9.7 billion cloud services contract with artificial intelligence cloud service provider IREN that will give it access to some of Nvidia's chips. The five-year deal, which includes a 20% prepayment, will help Microsoft as it looks to keep up with AI demand.

WORDS: 326 - MOVED: 11/03/2025 7:29 a.m. EST

https://newsroom.ap.org/detail/MicrosoftentersapproximatelyBcontractwithIRENthatgivesitaccesstoNvidiachips/b3d7a6032ad69dcbea43ce88b007fe3f/text

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EU--Romania-Germany

NATO member Romania signs agreement with Germany's Rheinmetall to build a gunpowder plant

SUMMARY: NATO member Romania has signed an agreement with Germany's defense company Rheinmetall to build a gunpowder factory in central Romania, as Europe races to rearm itself in the face of an increasingly provocative Russia. Prime Minister Ilie Bolojan hailed the joint venture between the Romanian state and Europe's largest arms producer as a sign that Romania is "emerging as a player with potential in the defense industry of Southeast Europe." Construction of the 535 million-euro ($616 million) plant in the town of Victoria in Brasov County is expected to start in 2026, take three years to complete and create 700 local jobs, he said.

WORDS: 283 - MOVED: 11/03/2025 7:00 a.m. EST

https://newsroom.ap.org/detail/NATOmemberRomaniasignsagreementwithGermanysRheinmetalltobuildagunpowderplant/2602bf077e3d0b6a0403d24153dbda0c/text

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US--Government-Shutdown-Aviation

Flight delays persist as government shutdown leads to air traffic controller shortages

SUMMARY: Flight delays are continuing at U.S. airports amid air traffic controller shortages as the government shutdown enters its second month. Newark airport in New Jersey was experiencing delays of two to three hours on Sunday. George Bush Intercontinental Airport in Houston, Dallas Fort Worth International Airport and Chicago O'Hare were also seeing dozens of delays and one or two cancellations. Other delays were being reported at major airports in Los Angeles and Miami.

WORDS: 457 - MOVED: 11/02/2025 1:32 p.m. EST

https://newsroom.ap.org/detail/Flightdelayspersistasgovernmentshutdownleadstoairtrafficcontrollershortages/538fcee7931eefed1acc50b104a67d1f/text

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<END>

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